$three hundred billion, private insurers paid the most important share ($112-$129 billion), government increases with age. Cp dominate sufferers' lives, causing disabilities in own family/domestic responsibilities, occupational, social, leisure, sleep and sexual activities. Ache-related investigations and treatments often make cp worse affecting sufferers' interactions with coworkers, physicians, own family and social community creating alienation and isolation. Constant ache interferes with capability to concentrate, impairs cognition with mood/memory changes from outcomes of medicines. International .